Pregnancy outcomes in Japanese pregnant women with either chronic hypertension or white coat hypertension (JP-WCH): protocol for a prospective multicenter cohort study

抄録

It is not known whether pregnant women with chronic hypertension (CH) develop preeclampsia (PE) more frequently than those with white coat hypertension (WCH). Therefore, we planned the following 2 studies: study 1 is a multicenter prospective observational study to distinguish WCH and CH, in (A) pregnant women with suspected hypertension with blood pressure measured in a clinical setting, and who had not been diagnosed with hypertension prior to the current pregnancy, and (B) pregnant women with a previous diagnosis of hypertension, but who have not received an accurate diagnosis specifying whether they have CH or WCH; study 2 is a multicenter retrospective cohort study, which will start after the recruitment of subjects in study 1, to compare the incidences of PE and gestational hypertension (GH) in women with WCH or CH. Here, we described a protocol for a prospective multicenter cohort study (JP-WCH study; UMIN study ID: UMIN000032790).