抄録
This research project has been organized facing the results of the international EC-IC bypass study, in which the effectiveness of the bypass surgery on stroke prevention could not be confirmed in the whole series, while a subgroup of Japan-Taiwan series revealed some benefits of surgery. The research project consists of main three pillars : 1. Newly designed randomized EC-IC bypass Japan cooperative study. 2. Further follow-up of entry cases of the international EC-IC bypass. 3. Individual research project by each investigator participating in the research project.
Newly designed randomized study has been initiated with a new entry criteria with emphasis on the hemodynamic dysfunction as shown in Table 2. Seventy two cases from 30 centers in Japan have entered the study through the end of Sept. 1991.
Individual research projects consists of followings : Projects on 1. Noninvasive, inexpensive, reliable and simple methods to detect hemodynamic dysfunction which is of cardinal importance in selecting candidates of reconstructive vascular surgery. 2. Less invasive, effective, safe, simple and longlasting methods of cerebrovascular reconstruction including the endovascular surgery. 3. Evaluation of the effectiveness of cerebrovascular reconstruction. 4. Experimental cerebral ischemia. 5. Any other items related with cerebrovascualr reconstruction.
