抄録
The usefulness of evidence-based medicine (EBM) has been discussed in various fields of clinical medicine. One method of the application of EBM is to make EBM-based clinical guideline for practitioners' clinical judgment.
In this communication, I presented the process of collecting clinical evidence to making the guideline for management of patients with cerebral infarction. This was done by research committee (Principal investingator : Yasuo Fukuuchi) on "Evidence-based Guideline for Patients with Cerebral Infarction ", which was supported by Japanese Ministry of Health, Labor and Warfare.
We collected about seventeen thousands literatures in English or Japanese on management of cerebral infarction, which were graded according the evidence levels. About six hundreds of these literatures were selected as high level of evidence, and stored in database.
Evidence in the database was summarized in each therapeutic item such as general management, neurological treatments, neurosurgical interventions and rehabilitation. Summaries of these items is not described here, which will be published in Annual Report 2002 of Japanese Ministry of Health, Labor and Warfare.
At present time, we have an insufficient amount of clinical evidence for making useful guideline for management of patients with cerebral infarction at acute and chronic stages.
