CT perfusionとCT angiographyを用いた急性期脳虚血性病変の評価

抄録

Ischemic stroke remains a common cause of death and disability in the industrialized world. In the treatment of ischemic stroke, conventional CT is still the primary imaging modality. However, positive CT findings do not appear during the narrow time window. There is a strong demand to establish a prompt diagnostic technique, which provides the cerebral perfusion information for the successful therapy. CT perfusion (CTP) is a new introduced image-processing technique which can provide quantitative cerebral blood flow by calculating functional maps such as cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT). CT angiography (CTA) has been also shown to be valuable for the detection of cerebral arterial occlusion and stenosis. Using multi-detector row CT, we performed both CTP and CTA as one time examination in the assessment of cerebral ischemia. In this symposium, we introduce our imaging protocols, and demonstrate the usefulness of combination diagnosis of CTP and CTP. The CTP and CTA are an accurate, convenient, and safe method in patients with cerebral ischemia. The combination diagnosis of CTP and CTA not only allows early detection of cerebral ischemia but also yields valuable information for planning management of acute ischemic stroke.