HVJとMumps Virusとの共通抗原性について 第2報

仙台市民 (1958-1959) のHVJ抗体の解析

抄録

To test the possibility of recent outbreak of Sendai virus infections among the population of Sendai, this serological survey was intended. Proposal of the work was originally made from the result reported in the previous paper, where most sera obtained from mumps patients at acute stag revealed high antibody titer against Sendai virus when tested in hemagglutination inhibition reaction.
An explanation of the fact was the shared antigen between these 2 viruses. An alternative idea was the anamestitic elicitation of Sendai virus antibody with mumps virus. However, both possibilities may finally lead to the same conclusion of shared antigen.
Serum specimens were obtained from 260 healthy people in Sendai and divided into two groups, i.e. one of children under 15 years, another of adult over 16 years old. The results obtained so far revealed the following conclusion.
1) 73% of children and 89% of adult did not have any antibody titer against Sendai virus when examined on hemagglutination inhibition test.
2) High distribution of antibody was found only among children between 4 and 10 years old. Antibody titer of these specimens was also high.
3) From 71 healthy children of 6 years old, new serum specimen were obtained to test the cross relationship of Sendai virus with mumps virus. 52% of the tested specimens had the titer against Sendai virus and 82% against mumps virus. Among 37 specimens positive against Sendai, 36 specimens (97%) had the significant titer against mumps virus. Whereas among 58 specimens positive agaiast mumps, 36 (62%) was positive against Sendai virus. Taken together, HAI titer revealed here against Sendai virus was anticipated to have the character provoked by mumps virus. However, critical analysis of this observation was left for further studies