ポリオウイルスとコクサキーウイルスの干渉現象に関する研究 (III)

ポリオウイルスとコクナキーウイルスの干渉現象とギランバレー症候群との関係

抄録

As shown in the preceeding papers, it was revealed that the coxsackie virus isolated from the patient with typical Guillain-Barré syndrome Okumoto strain interfered the polio Lansing strain. The possible interpretation on the production of the syndrom on the basis of interference phenomena was sought in analysing the histopathological picture in this report. The involvement of the interfered case exhibited the indiscernible features produced by the single infection of coxsackie virus or polio virus independently which is dissimilar to the actual changes observed by Guillain-Barrè syndrome. The extent of the involvement of the mice without significant signs of paralysis revealed no changes or of minor degree in the site. The interference would seem to be produced prepathological level between polio and coxsackie virus.