1987 年 4 巻 p. 49-54
In summary, although nemerous studies in different animal species and humans have provided evidence for an essential role of zinc in vitamin A metabolism, there remains a need for well-control double-blind intervention studies. Ideally, the investigations would involve subjects free of chronic diseses without severe malnutrition. In addition, the subjects should exhibit suboptimal status of both zinc and vitamin A. The impaired nutriture should first be documented by a combination of biochemical and functional parameters. Preliminary survey in NE Thailand indicates a prevalence of combined inadequacies of both zinc and vitamin A, a result of insufficient dietary intake of these nutrients.