Abstract
Detoxication of bis (2-hydroxy-3, 5-dichlorophenyl) sulfide, bithionol, was investigated in man. A novel metabolite was isolated as a crystalline derivative from bithionol medicated urine and identified as bithionol-monoglucuronide (as a methyl acetyl derivative). Oxidation of the sulfur atom of this compound was not recognized It is concluded that bithionol is detoxicated partially by forming a monoglucuronide conjugate.
