Abstract
Immunoresponse is a highly systematized homeostatic regulation mechanism exhibited by all vertebrate classes, and its variability is closely related to the phylogenetic development of the animal species. Now, the immunoresponse is also understood as the major function of lymphocytes strictly controlled by the genetic properties of individuals. The specific interactions of the immune system with vast kinds of antigens occur through the variable regions of amino acid sequence of the receptor antibody molecules on lymphocytes and each of the variable regions carries a particular set of antigenic determinants which is termed "Idiotype".
As background to some of the recent works in these research fields, in this article, some of the fundamental facts about the immunoglobulin molecule involving the receptor antibody on lymphocyte surface as the specificity determining and regulating factors for immunoresponse were briefly summerized.
