抄録
Antimicrobial agents are essential for human and animal health and welfare, but antimicrobial use can lead to antimicrobial resistance. The resistance arising from antimicrobial use in food-producing animals represents a potential hazard to human medicine through foodborne infection caused by resistant bacteria. In Japan, the Japanese Veterinary Antimicrobial Resistance Monitoring System (JVARM) was formed in 1999 in response to international concern about the impact of antimicrobial resistance on public health. In the JVARM program, initial monitoring for antimicrobial-resistant bacteria was carried out in 1999 and then the first and second stages of the JVARM program were completed in 2000-2003 and 2004-2007, respectively.
Veterinary antimicrobial use is a selective force for appearance and prevalence of antimicrobial-resistant bacteria in food-producing animals. However, antimicrobial-resistant bacteria are found in the absence of antimicrobial selective pressure. We show here the relationship between antimicrobial usage and prevalence of resistant bacteria under the JVARM from 1999 to 2007.
