抄録
In this time, I reviewed epidemiology of antimicrobial-resistant bacteria isolated from companion animals. In Enterobacteriaceae, Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp. relatively frequently exhibited resistance to extended-spectrum cephalosporins and fluoroquinolones. Most of the ESC-resistant isolates harbored extended-spectrum β-lactamases (ESBLs). Some of the ESBL-producing isolates were genetically related and detected in specific veterinary hospitals. On the other hand, more than half of Proteus mirabilis isolates were susceptible to the tested antimicrobials. Most of Pseudomonas aeruginosa isolates were highly susceptible against most of antipseudomonal drugs, except for fluoroquinolones. In Staphylococcus pseudintermedius, methicillin-resistant isolates, exhibiting resistance against multiple drugs, become prevalent, especially in secondary medical hospital. In Enterococci, isolates from animals with antimicrobial exposure were more resistant to several antimicrobials, compared with those without antimicrobial exposure. Overall, in companion animals, ESBL-producing Enterobacteriaceae and methicillin-resistant S. pseudintermedius have been prevalent and, thus continuous monitoring would be needed to understand the trend of these antimicrobial-resistant bacteria.
