1977 年 30 巻 7 号 p. 374-380
In November, 1975, some adult sheep produced in Japan began to suffer from fever, anemia, palpitation, tachypnea, and hemoglobinuria. Light and electron microscopy revealed that many parasitic organism of Eperythrozoon ovis were present on the surface of erythrocytes. With an increase in parasitic rate, the erythrocyte count, hematocrit, and hemoglobin values decreased, erythrocytic resistance was reduced, and hemoglobin plasma appeared.
When a splenectomized and an intact sheep were inoculated with blood from a spontaneously infected sheep, Ep. ovis began to appear in their peripheral blood 10 and 12 days after inoculation, respectively. The inoculated sheep manifested the same clinical signs and hematological changes as the spontaneously infected one. This report was the first to confirm the presence of Ep. ovis in Japan.