Abstract
Spontaneous systemic lymphosarcoma was found in a 5-year-old Corriedale sheep, showing a marked weight loss. Necropsy revealed a huge tumor located in the anterior mediastinum associated with enlargements of the cervical lymphonode. There were milky white masses in the pars costalis of the diaphragm, jejunum, lymphonodi jejunales, and liver. Histologically, large round tumor cells exhibited a diffuse proliferation, containing a round to irregular-shaped nucleus with indentation or distortion. This case was diagnosed as thymic, diffuselymphosarcoma of large cell type.