Magnetic Resonance Imaging and Histopathology of Encephalitis in a Pug

Abstract

A female 3-year-old Pug showing frequent epileptic fits during 8-months was shown on magnetic resonance imaging (MRI) to have dilated cerebral ventricles and inflammatory lesions in the whole cortex of the bilateral cerebral hemispheres as well as the lower left parietal and the middle right temporal lobes. Histopathology of the corresponding regions revealed meningoencepalitis characterized by wide distribution of degenerated neurons with glial satellitosis and neuronophagia and prominent perivascular cuffing with lymphoid cells.