Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Malignant Fibrous Histiocytoma (MFH) Cells and Macrophages/Histiocytes Have a Common Antigen Recognized by a Monoclonal Antibody Risen against a Rat MFH-Derived Cloned Cell Line
Daijiro KUMAGAIJyoji YAMATETomoko TAJIMAMitsuru KUWAMURATakao KOTANISadashige SAKUMA
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2001 Volume 63 Issue 3 Pages 333-335

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Abstract

A monoclonal antibody (B9) was generated by using a rat malignant fibrous histiocytoma (MFH)-derived cloned cell line (MT-8) as the immunogen. Immunohistochemically, B9 reacted specifically with a cytoplasmic antigen of MT-8 cells. Furthermore, B9 immunolabeled another MFH-derived cloned cells (MT-9) and histiocytic sarcoma cells, as well as macrophages/histiocytes in normal and diseased tissues of rats. These findings suggest the presence of a common antigen recognized by B9 between MFH cells and macrophages/histiocytes. This suggests that MFH cells may express histiocytic nature.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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