Molecular Clonings and Sequences of Djungarian (Phodopus sungorus) and Chinese (Cricetulus griseus) Hamster Interferon-Gammas

Abstract

Djungarian (Phodopus sungorus) and Chinese (Cricetulus griseus) hamster IFN-γ genes were cloned and sequenced. The Djungarian and Chinese hamster genes were both 525bp nucleotides, resulting in 174 amino acids in full length with a predicted molecular weight (MW) of 19,560 dal and 19,775 dal, respectively. The first 23 amino terminal amino acids consisted of a hydrophobic signal sequence when cleavaged, which would result in a mature 151 amino acid polypeptide with a predicted MW of 17,115 dal in the Djungarian hamster IFN-γ and 17,255 dal in the Chinese hamster one.