Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
NOTE
Immunohistochemical Detection of Growth Hormone (GH) in Canine Hepatoid Gland Tumors
Claudio PETTERINOMarco MARTINIMassimo CASTAGNARO
Author information
JOURNALS FREE ACCESS

2004 Volume 66 Issue 5 Pages 569-572

Details
Abstract

The aim of this study was to detect immunohistochemically means growth hormone (GH) in 24 hepatoid gland adenomas and 5 hepatoid gland carcinomas and to compare the difference of immunoreactivity between types of tumors. The tumors were classified according to the WHO standards. Tissue sections which were prepared from formalin-fixed, paraffin wax-embedded tissues from 25 male and 4 female dogs were carried out immunostaining using polyclonal primary anti-hGH and EnVision method. Of 24 hepatoid gland adenomas (perianal gland adenomas) 23 (95.8%) were positive. All 5 hepatoid gland carcinomas (perianal gland carcinomas) were positive. No statistically significant differences in percentage of labelled cells between malignant and benign tumors were seen. The present demonstration of GH in hepatoid gland tumors adds new data on GH in extra-pituitary tissues and hormon-dependent tumors.

Information related to the author
Previous article Next article
feedback
Top