Increase of Antibody Titer against Leucocytozoon caulleryi by Oral Administration of Recombinant R7 Antigen

Akira ITO; Tohru GOTANDA; Shigeki KOBAYASHI; Katsumi KUME; Chihiro SUGIMOTO; Takeshi MATSUMURA

doi:10.1292/jvms.67.211

NOTE

Increase of Antibody Titer against Leucocytozoon caulleryi by Oral Administration of Recombinant R7 Antigen

Akira ITO, Tohru GOTANDA, Shigeki KOBAYASHI, Katsumi KUME, Chihiro SUGIMOTO, Takeshi MATSUMURA

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Keywords: Leucocytozoon caulleryi, oral administration, recombinant R7 antigen

JOURNAL FREE ACCESS

2005 Volume 67 Issue 2 Pages 211-213

DOI https://doi.org/10.1292/jvms.67.211

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Abstract

In this study, we examined oral administration with recombinant R7 (rR7) antigen expressed in Escherichia coli using chicken leucocytozoonosis subunit vaccine (LV)-vaccinated and unvaccinated chickens. Only LV-vaccinated chickens showed re-induction of anti-second-generation schizont (2GS) antibody. Also, LV-vaccinated chickens whose anti-2GS antibody titer was middle-level showed increases of the antibody titer compared to vaccinated-control chickens (P>0.01, >0.05) after oral administration with rR7 antigen.

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