In vitro Enhancement by CpG ODN of Phagocytic Activity of Rainbow Trout Head Kidney Phagocytes against Fish Pathogen Vibrio ordalii, but not against Polystyrene Particles

Masahiro NAKATANI; Tadashi IWASAKI; Shinobu WATARAI; Hiroshi KODAMA

doi:10.1292/jvms.69.1287

Immunology

In vitro Enhancement by CpG ODN of Phagocytic Activity of Rainbow Trout Head Kidney Phagocytes against Fish Pathogen Vibrio ordalii, but not against Polystyrene Particles

Masahiro NAKATANI, Tadashi IWASAKI, Shinobu WATARAI, Hiroshi KODAMA

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Keywords: CpG ODN, innate immunity, rainbow trout, head kidney phagocytes

JOURNAL FREE ACCESS

2007 Volume 69 Issue 12 Pages 1287-1290

DOI https://doi.org/10.1292/jvms.69.1287

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Abstract

Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity agaist Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.

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