Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
NOTE
A Case of Hyperplastic Dermatosis of the West Highland White Terrier Controlled by Recombinant Canine Interferon-γ Therapy
Koji NISHIFUJISeong-Jun PARKToshiroh IWASAKI
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2007 年 69 巻 4 号 p. 455-457

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A 3.5-year-old, male West Highland White Terrier was diagnosed as having hyperplastic dermatosis by clinical and histopathological findings. Controlling of Malassezia overgrowth by antifungal drugs provided a temporal improvement of the skin lesions, but the disease was deteriorated within the next 2 months despite the negative demonstration of the yeasts. Induction of recombinant canine interferon-γ (rCaIFN-γ) therapy resulted in almost complete cure of the skin lesions within 2 months after the initiation of the therapy. No adverse effects were detected during the therapy. Our results suggested that the rCaIFN-γ therapy is potential to be a novel therapeutic option for controlling the breed-specific hyperplastic skin disease.

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© 2007 by the Japanese Society of Veterinary Science

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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