Characterization of Canine Platelet Activation Induced by Platelet Activating Factor (PAF)

Journal of Veterinary Medical Science

Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250

Clinical Pathology

Characterization of Canine Platelet Activation Induced by Platelet Activating Factor (PAF)

Ryo TSUCHIYA, Yumiko TATSUKI, Satoshi KITAO, Mitsuru FURUICHI, Sakurako NEO, Masaharu HISASUE, Takatsugu YAMADA, Kosaku KOBAYASHI

著者情報

キーワード: canine platelet, inhibitor, platelet activating factor

ジャーナルフリー

2008 年 70 巻 2 号 p. 181-183

DOI https://doi.org/10.1292/jvms.70.181

詳細

抄録

Characteristics of the signal transduction in Platelet activating factor (PAF)-activated platelets and effects of anti-platelet agents on this response were investigated in vitro for potential therapeutic applications in canine endotoxemia. Blockade of the PAF receptor by a specific blocker has the strongest inhibitive effect on the PAF-induced platelet reactions. The response was also inhibited by either Ca²⁺ channel blockers or prostaglandin E₁.

著者関連情報

© 2008 by the Japanese Society of Veterinary Science

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja

お気に入り & アラート

関連記事

閲覧履歴

前身誌

大日本獸醫會誌

中央獸醫會雑誌

日本獸醫學會雑誌

應用獸醫學雑誌

中央獸醫學雑誌

日本獸醫學雜誌(The Japanese Journal of Veterinary Science)

Top