The full genome sequences of 8 equine herpesvirus type 4 isolates from horses in Japan

Satoko IZUME; Rikio KIRISAWA; Kenji OHYA; Aiko OHNUMA; Takashi KIMURA; Tsutomu OMATSU; Yukie KATAYAMA; Tetsuya MIZUTANI; Hideto FUKUSHI

doi:10.1292/jvms.16-0506

Virology

The full genome sequences of 8 equine herpesvirus type 4 isolates from horses in Japan

Satoko IZUME, Rikio KIRISAWA, Kenji OHYA, Aiko OHNUMA, Takashi KIMURA, Tsutomu OMATSU, Yukie KATAYAMA, Tetsuya MIZUTANI, Hideto FUKUSHI

著者情報

Satoko IZUME
Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan
Rikio KIRISAWA
Laboratory of Veterinary Virology, Department of Pathobiology, School of Veterinary Medicine, Rakuno Gakuen University, 582 Bunkyoudai Midori-machi, Ebetsu, Hokkaido 069–8501, Japan
Kenji OHYA
Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan
Laboratory of Veterinary Microbiology, Faculty of Applied Biological Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan
Aiko OHNUMA
Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University, West 9 North 18, Kita-ku, Sapporo 060-0818, Japan
Takashi KIMURA
Laboratory of Comparative Pathology, Graduate School of Veterinary Medicine, Hokkaido University, West 9 North 18, Kita-ku, Sapporo 060-0818, Japan
Tsutomu OMATSU
Research and Education Center for Prevention of Global Infectious Disease of Animal, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan
Yukie KATAYAMA
Research and Education Center for Prevention of Global Infectious Disease of Animal, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan
Tetsuya MIZUTANI
Research and Education Center for Prevention of Global Infectious Disease of Animal, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan
Hideto FUKUSHI
Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences, Gifu University, 1–1 Yanagido, Gifu 501–1193, Japan

キーワード: abortion, genome sequence, Japanese equine herpesvirus type 4

ジャーナルフリー
電子付録

2017 年 79 巻 1 号 p. 206-212

DOI https://doi.org/10.1292/jvms.16-0506

Browse “Advance online publication” version

詳細

抄録

Equine herpesvirus type 4 (EHV-4) is one of the most important pathogens in horses. To clarify the key genes of the EHV-4 genome that cause abortion in female horses, we determined the whole genome sequences of a laboratory strain and 7 Japanese EHV-4 isolates that were isolated from 2 aborted fetuses and nasal swabs of 5 horses with respiratory disease. The full genome sequences and predicted amino acid sequences of each gene of these isolates were compared with of the reference EHV-4 strain NS80567 and Australian isolates that were reported in 2015. The EHV-4 isolates clustered in 2 groups which did not reflect their pathogenicity. A comparison of the predicted amino acid sequences of the genes did not reveal any genes that were associated with EHV-4-induced abortion.

責任著者(Corresponding author)

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