Therapeutic effects of oral clomiphene citrate in 2 dogs with low plasma testosterone levels and poor semen quality

Abstract

Two dogs with low plasma testosterone (T) levels and poor semen quality were administered one tablet of 12.5 mg clomiphene citrate orally per day at 2-day intervals for 4 weeks. Plasma T levels, total sperm count, and sperm motility in both dogs temporarily increased between 3 and 6 weeks after the start of treatment. These results indicate that poor semen quality in dogs with low plasma T level can be improved by oral administration of clomiphene citrate.