Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Virology
First detection of NADC34-like porcine reproductive and respiratory syndrome virus strains in Japan
Yoriko YONEZAWAOsamu TAIRATakashi OMORINobuyuki TSUTSUMIKatsuaki SUGIURA
Author information
JOURNAL OPEN ACCESS

2025 Volume 87 Issue 1 Pages 110-114

Details
Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) is an important pathogen in the swine industry. We report for the first time the detection of NADC34-like PRRSV strains in Japan. Serum samples from 18 piglets in Okinawa Prefecture were analyzed for the open reading frame 5 (ORF5) gene encoding glycoprotein 5, which revealed that all samples belonged to sublineage 1.5 (L1A) of Lineage 1. Phylogenetic analysis, restriction fragment length polymorphism patterns, and glycosylation site characteristics confirmed the presence of NADC34-like strains that caused severe outbreaks in the U.S. and Asia. Despite its known pathogenicity, the farm showed only a transient increase in mortality. These findings highlight the need for further investigation into the pathogenicity of PRRSV strains and their potential for the emergence of new variants in Japan.

Content from these authors
© 2025 by the Japanese Society of Veterinary Science

This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
https://creativecommons.org/licenses/by-nc-nd/4.0/
Previous article Next article
feedback
Top