Two Cases of Bovine Male Pseudohermaphrodites with Different Endocrinological and Pathological Findings

Abstract

Two cases of bovine male pseudohermaphrodites (PH) were subjected for clinical investigation with transrectal ultrasonography, endocrinology with adoption of hCG-stimulation test, cytogenetics with analysis of sex chromosome and Y-specific DNA, and finally histological examination. Results were compared with normal calves. Case 1 was a 10-mo-old calf with XX/XY chimeras, showing elevation of testosterone (T) levels, but no change in progesterone (P₄) after hCG test, and possessed atrophied testes in the cavitas pelvis. Case 2 was an 18-mo-old calf with SRY positive-XY chromosome, showing lower level of plasma T and P₄ after hCG test, and possessed atrophied testes and undifferentiated genital ducts. Both cases possessed female-like external genitalia with similar pathological findings, however endocrinological and cytogenetical aspects were different each other.