Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250

This article has now been updated. Please use the final version.

Skin Conductance Reflects Drug-Induced Changes in Blood Levels of Cortisol, Adrenaline, and Noradrenaline in Dogs
Maki ISHIBASHIHideo AKIYOSHIToshie ISERIFumihito OHASHI
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JOURNAL FREE ACCESS Advance online publication

Article ID: 12-0478

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Abstract
To verify availability of skin conductance (SC) as an indicator for the sympathetic nervous system (SNS) activity in dogs, the changes of SC and blood levels of stress-related hormones induced by drugs were compared. SC and cortisol, adrenaline and noradrenaline levels were measured in 5 dogs on 4 occasions with or without drug-induced sedation at 7 day-intervals (no treatment, intramuscular medetomidine 0.01 mg/kg, intramuscular acepromazine 0.1 mg/kg, and intravenous fentanyl 0.02 mg/kg). The fentanyl treatment produced significant higher levels of SC and plasma cortisol and adrenaline, compared with the other 3 treatments. The plasma noradrenaline level also tended to be higher following the fentanyl treatment. These results indicate that SC may reflect changes in the SNS activities in dogs.
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© 2013 by the Japanese Society of Veterinary Science

この記事はクリエイティブ・コモンズ [表示 - 非営利 - 改変禁止 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
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