Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders

Masaya IGASE; Takako SHIMOKAWA MIYAMA; Satoshi KAMBAYASHI; Yumiko SHIMOYAMA; Hiroko HIRAOKA; Yumi HIRATA; Miki IWATA; Kenji BABA; Takuya MIZUNO; Masaru OKUDA

doi:10.1292/jvms.15-0156

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Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders

Masaya IGASE, Takako SHIMOKAWA MIYAMA, Satoshi KAMBAYASHI, Yumiko SHIMOYAMA, Hiroko HIRAOKA, Yumi HIRATA, Miki IWATA, Kenji BABA, Takuya MIZUNO, Masaru OKUDA

著者情報

キーワード: feline, hyperproteinemia, immunofixation, oncology, plasma cell disorders

ジャーナルフリー早期公開

論文ID: 15-0156

DOI https://doi.org/10.1292/jvms.15-0156

この記事には本公開記事があります。

The final version of this article is now available: Vol. 78 (2016), No. 4 pp. 691-695

詳細

抄録

A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb-was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat died due to renal failure. Postmortem immunohistopathologic evaluation of the subcutaneous mass revealed neoplastic cell proliferation of plasma cells and giant myeloma cells. Neoplastic cells were also present in the liver and spleen. These results led to the diagnosis of a rare case of feline myeloma-related disorders with extramedullary plasmacytoma infiltrating in multiple locations. This report emphasizes the necessity to accumulate cases with similar clinicopathologic findings in the future.

責任著者(Corresponding author)

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