Detection of felis catus papillomavirus type 3 and 4 DNA from squamous cell carcinoma cases of cats in Japan

Nanako YAMASHITA-KAWANISHI; Ryoma SAWANOBORI; Kosuke MATSUMIYA; Akiko UEMA; James K. CHAMBERS; Kazuyuki UCHIDA; Hidekatsu SHIMAKURA; Masano TSUZUKI; Chia-Yu CHANG; Hui-Wen CHANG; Takeshi HAGA

doi:10.1292/jvms.18-0089

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Detection of felis catus papillomavirus type 3 and 4 DNA from squamous cell carcinoma cases of cats in Japan

Nanako YAMASHITA-KAWANISHI, Ryoma SAWANOBORI, Kosuke MATSUMIYA, Akiko UEMA, James K. CHAMBERS, Kazuyuki UCHIDA, Hidekatsu SHIMAKURA, Masano TSUZUKI, Chia-Yu CHANG, Hui-Wen CHANG, Takeshi HAGA

著者情報

Nanako YAMASHITA-KAWANISHI
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Ryoma SAWANOBORI
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Kosuke MATSUMIYA
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Akiko UEMA
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
James K. CHAMBERS
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Kazuyuki UCHIDA
Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Hidekatsu SHIMAKURA
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Masano TSUZUKI
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Chia-Yu CHANG
Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University
Hui-Wen CHANG
Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University
Takeshi HAGA
Division of Infection Control and Disease Prevention, Graduate School of Agricultural and Life Sciences, The University of Tokyo

キーワード: FcaPV type 3, FcaPV type 4, feline squamous cell carcinoma, Japan, type specific primer

ジャーナルフリー早期公開

論文ID: 18-0089

DOI https://doi.org/10.1292/jvms.18-0089

この記事には本公開記事があります。

The final version of this article is now available: Vol. 80 (2018), No. 8 pp. 1236-1240

詳細

抄録

Association of felis catus papillomaviruses (FcaPVs) with feline squamous cell carcinoma (SCC) has been reported worldwide, while there is limited information about FcaPVs in Asia. In this study, 21 feline SCC biopsy samples from cats in Japan were analyzed by PCR with PV consensus primers and type-specific primers for FcaPV type 2 (FcaPV-2), FcaPV-3 and FcaPV-4 designed in this study. Sequence analysis revealed that one sample was FcaPV-3, and two were FcaPV-4. In both FcaPV-4 positive samples, 334th tryptophan in L1 ORF was deleted compared with the reference sequence. Moreover, immunohistochemistry showed that p16 protein was positive in both FcaPV-4 detected samples. This study would contribute to the molecular epidemiological and pathological understanding of FcaPV in Japan.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）