Changes in the C-reactive protein and 13,14-dihydro-15-keto-prostaglandin F2α concentrations of uterine lavage samples after the administration of povidone-iodine in cows

Yuki ANDO; Dai ISHIYAMA; Hideshige SHIMIZU; Natsumi ENDO; Tomomi TANAKA

doi:10.1292/jvms.22-0249

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Changes in the C-reactive protein and 13,14-dihydro-15-keto-prostaglandin F_2α concentrations of uterine lavage samples after the administration of povidone-iodine in cows

Yuki ANDO, Dai ISHIYAMA, Hideshige SHIMIZU, Natsumi ENDO, Tomomi TANAKA

著者情報

キーワード: 13,14-dihydro-15-keto-prostaglandin F_2α, bovine uterine lavage, C-reactive protein, inflammation, povidone-iodine

ジャーナルオープンアクセス早期公開

論文ID: 22-0249

DOI https://doi.org/10.1292/jvms.22-0249

この記事には本公開記事があります。

The final version of this article is now available: Vol. 84 (2022), No. 10 pp. 1373-1376

詳細

抄録

Changes in the C-reactive protein (CRP) and 13,14-dihydro-15-keto-prostaglandin F_2α (PGFM) concentrations of uterine lavage fluid were examined in cows given an intrauterine povidone-iodine (PI) infusion. The mean polymorphonuclear leukocyte (PMN) ratios (the ratio of PMN to total cells) and CRP concentration of uterine lavage fluid on the day after the treatment were significantly (P<0.05) greater in the PI infusion group (PMN: 53.0 ± 32.7%, CRP: 50.2 ± 32.3 ng/mL) than in the non-treatment control group (PMN: 7.9 ± 21.9%, CRP: 17.2 ± 5.9 ng/mL), whereas there was no significant difference in the mean PGFM concentration between the two groups. The present findings suggest that the uterine CRP level is a useful biomarker of local uterine inflammation in cows.

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