抄録
Pathological studies were carried out on laryngotracheal and conjunctivallesions caused by experimental infection with so-called Asian type Newcastle disease virus.In them, strain 2440 of the virus was inoculated into two groups of chickens by the intra-tracheal and intra-ocular route. The same symptoms and gross lesions as those of theacute type in field outbreaks were observed in the birds of both groups during 3 to 6 daysafter inoculation. Prominent necrosis of the epithelium and lymphatic areas and mildto moderate proliferation of lymphoid cells were seen as characteristic changes in theorgans studied. The course of epithelial necrosis was initiated by vacuolation of thecytoplasm, followed by the appearance of eosinophilic inclusions and the formation of anetwork inside the cytoplasm and terminated by the disintegration of epithelial cells intodebris. Necrosis of the lymphoid area was similar to the change of lymphatic organspreviously reported by this author.
