Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Studies on Closure of the Ductus Arteriosus in Perinatal Rats
Tatsuya TAKIZAWAKazuyoshi ARISHIMAMasako YAMAMOTOMasahiko KUSANAGIHiroaki SOMIYAYasunobu EGUCHI
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1992 Volume 54 Issue 6 Pages 1195-1198

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Abstract
Measurements of the inner diameters (calibers) of the ductus arteriosus (DA) and pulmonary artery (PA) were made in late fetal rats and newborn rats, the latter being obtained by spontaneous or caesarean delivery. The fetal and newborn pups were frozen instantly with an acetone-dry ice mixture. The chests of these whole-body frozen pups were shaved with a surgical knife gradually from the back toward the ventral side to expose the DA and PA for measurements of their calibers. As a result, it was revealed that the DA was almost closed 180 min after birth, but that the closure and shirinkage of the DA were accelerated to some extent by caesarean delivery. On the other hand, there was no remarkable change in the PA throughout the postnatal period observed, regardless of the type of delivery, spontaneous or caesarean.
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© The Japanese Society of Veterinary Science
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