Journal of Veterinary Medical Science
Online ISSN : 1347-7439
Print ISSN : 0916-7250
ISSN-L : 0916-7250
Toxicity and Properties of the Extract from Sarcocystis cruzi Cysts
Morihiro SAITOKiyoaki TAGUCHIYutaka SHIBATATakayuki KOBAYASHIKameo SHIMURAHiroshi ITAGAKI
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JOURNAL FREE ACCESS

1995 Volume 57 Issue 6 Pages 1049-1051

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Abstract
The extract from Sarcocystis cruzi cysts in bovine muscle was subcutaneously injected to mice, guinea pigs, chickens, and rabbits to detect its toxicity. Only rabbits showed reactions after administration of the extract at a dose of 25 μg. The main clinical signs of the rabbits were depression, reduction in body temperature and intermittent diarrhea and the hematological findings observed were elevation in WBC, RBC, PCV, TP, BUN, AST, AUT and creatinine values and reduction in glucose, K+ and pH of blood. The extract, crude toxin, was a water soluble, acid-alkali stable and thermolabile protein and estimated to be a molecular mass of 15-16 kd.
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© The Japanese Society of Veterinary Science
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