COVID-19罹患中に分娩に至った妊婦3症例の検討

抄録

Herein, we report three pregnant women who gave birth while suffering from coronavirus disease 2019 (COVID-19). All of the newborns tested negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at birth and 48 hours later. In all of these cases, the main issues were how long to continue breastfeeding restrictions and mother-infant separation after delivery. With reference to prior reports, we examined the measures taken in each case. In case 1, breastfeeding restriction and mother-infant separation were continued until the patient satisfied the COVID-19 discharge criteria of the Ministry of Health, Labour and Welfare, and her nasopharyngeal SARS-CoV-2 polymerase chain reaction (PCR) test result was negative. However, since the nasopharyngeal SARS-CoV-2 PCR test result can be positive for a long period of time, we thought that it would be impractical to restrict breastfeeding or to continue mother-infant separation until the test results were confirmed to be negative in all cases. Thus, in the other cases, SARS-CoV-2 PCR testing of the breast milk was conducted once it was produced, and indirect breastfeeding was performed after the test results were negative. Mother-infant separation was discontinued after the nasopharyngeal SARS-CoV-2 qualitative antigen test result was negative, and the infants did not develop any COVID-19 symptoms. It has been reported that breast milk from mothers with COVID-19 is more likely to contain SARS-CoV-2-specific antibodies. In the future, we will investigate the possibility of shortening the mother-infant separation period by early initiation of breastfeeding.