薬剤耐性大腸菌の分布に関する研究

抄録

The distribution of drug-resistant E. coli was surveyed on 1560 persons, including healthy persons, dysentery-patients and carriers, during the period from November, 1959 to March, 1960.
For the isolation of drug-resistant strains of E, coli were used Mac Conkey's agar plates containing either chloramphenicol or tetracycline in the concentration of 25 mcg/ml.
The resistant strains of E. coli were isolated from 158 out of 1560 persons, that is, in 9.7%
In the group of healthy persons, the carriers of resistant E. coli were 137 out of 1474 cases (9.2%).
The resistant E. coli was isolated from 15 out of 70 cases (21.4%) in the group of dysentery-patients and carriers who excreted sensitive Shigella. On the other hand, in the group of dysentery-patients and carriers who excreted resistant shigella, the resistant strains of E. coli were isolated from 6 out of 16 cases (37.5%).
Of 158 resistant strain of E. coli, 70 strains (44.3%) were multiple-resistant to drugs such as streptomycin, chloramphenicol, tetracycline and sulfonamide, and the remaining 88 strains were found resistant only to tetracycline.