S-6436の治療効果
1977 年 51 巻 6 号 p. 312-316
詳細
1977 年 51 巻 6 号 p. 312-316
S-6436 is a new long-acting preparation of Cephalexin. This report describes the clinical trial with this drug.
S-6436 was administered at the dose 500mg b.i.d. after meal. Clinical results of S-6436 in 18 cases of respiratory tract infections were excellent in 2 cases, good in 11 cases, slightly good in 3 cases and failure in 2 cases. In 7 cases in urinary tract infections, clinical results obtained were excellent in 1 case, good in 5 cases and slightly good in 1 case. Transient and slight increase of S-GOT and S-GPT was noted in 1 case, and S-GPT in 1 case.
It is considered that S-6436 and Cephalexin are equal in points of effectiveness and safety in the treatment of mild or moderately severe infections. Therefore, S-6436 of 500mg b.i.d. after meal may be more advantageous for the patients than Cephalexin 250mg q.i.d.
