We reporta case of leptospirostihsa t was diagnosedi n the earlys tage of infection by using flaB-PCR. The flaB gene of Leptospira was amplifiedf rom the DNA extract of the patient'sb lood at hospital day 1, while leptospiraaln tibody was negative by the method of microscopica gglutination test and micocapsulea gglutinatiotne sta t that time. Seroconversion occurred at hospital day 6 and Leptospira was isolatefdr om the patient's blood at hospital day 16, demonstrating that flaB-PCR method was very usefuli uearly diagnosios of leptospirosis.
