抄録
The present study was undertaken to investigate the biochemical characteristics of collagen in the capsule and skin from patients with Ehlers-Danlos syndrome ( E-D ).
1. Collagen was extracted from human joint capsule and skin in 2 case s with E-D aged 26 and 38years old.
2. The amounts of collagen in the joint capsules; 10-15 %, the skin; 20-25 % per tissue wet weight.
3. The amount of soluble collagen in the joint capsules and the skin were 1.5-2.0 %.
4. The amounts of reducible cross-links in every tissue were richer in E-D thas in th e L-S. But the skin results were similar to those in the L-S with a re-operation.
5. These data were different from the biochemical c hanges of collagen in canine joint capsules and muscles in traumatic dislocations.
6. These suggest that the biochemical characteristics of collagen in the L-S are similar to those in E-D, especially in the L-S with a re-operation.
