抄録
In view of these facts, we undertook to examine the tooth and the adjacent tissues in albino rats which were given cortisone acetate and were subjected to severe degenerative atrophy in the adrenal cortex. Results ; 1. The adreno-cortical degeneration caused by over dosage or continual dosage of the hormone proved eventually fatal to the animal. 2. The histological findings in the tooth and the surrounding tissues by cortisone administration closely resembled to those found by hypophysectomy. The main findings were circulatory disturbance followed by degenerative changes which affected the developmental process of hard tissue, resulting in particular in the disturbed calcification of dentine.
