1991 年 57 巻 544 号 p. 3077-3082
A qualitative model on the remodeling of soft connective tissues is proposed, from which follows that the dynamic component of tensile strain will induce the strengthening of tissues and the static component of them will induce lengthening of tissues. Based on this hypotheses, we examine the design rule for elastic prostheses, the use of them insure the proliferation and the maturity of reconstructed tissues surrounding the prostheses. Then we construct artificial ligaments for rabbit's anterior cruciate, and carried out animal experiments. Unfortunately, considerable inflammation responses are induced, the wear debris are supposed to be responsible for.