The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
EXTREMELY PROFOUND HYPOTHERMIA WITHOUT BLOOD BY MEANS OF EXCHANGE PERFUSION OF THE BLOOD SUBSTITUTE
PRELIMINARY REPORT
TATSUYUKI KUDO
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JOURNAL FREE ACCESS

1963 Volume 12 Issue 1 Pages 1-8

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Abstract

This new method of prolonged total body circulatory interruption is devised under extremely profound hypothermia by means of the exchange perfusion of a blood substitute using extracorporeal circulatory machine.
There are several significances of this method:
1) Prolonged total body circulatory interruption is obtained.
2) Temperature near 0°C is obtained very rapidly.
3) An absolutely bloodless surgical field is secured under this condition.
4) No sequelae are noticed after recovery.
5) No blood is perfused during the cooling period. This procedure facilitates high flow and rapid cooling.
6) A great future is expected to perform a riskful operation radically and safely under this new method.

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