The Keio Journal of Medicine
Online ISSN : 1880-1293
Print ISSN : 0022-9717
ISSN-L : 0022-9717
CYTOSPECTROPHOTOMETRIC STUDIES ON THE ERYTHROCYTES IN LEUCEMIA AND APLASTIC ANEMIA
TADAYOSHI KOBAYASHIHIROSHI WATANABE
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1955 Volume 4 Issue 3 Pages 135-142

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Abstract
The erythrocytes of the normal people and various anemic patients are studied cytospectrophotometrically and the following results are obtained.
1. The absorption curve of erythrocytes can be identified with the spectra of hemoglobin as an intense peak which is found to be Soret band.
2. The erythrocytes in aplastic anemia show the different absorption curves from these in the other cases.
3. On the other hand, the erythrocytes in leucemia and the other diseases have slight differences of absorption curves from normal ones. Namely, the most intense absorption tendents to be lower.
4. Accordingly the erythrocytes in aplastic anemia are cytospectrophoto-metrically distinct from those in leucemia.
5. These cytospectrophotometric data are compared with the pathological findings of autopsy cases.
6. The nature of aplastic anemia is discussed from the view-point of intracellular structure of hemoglobin.
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