The effect of recombinant human granulocytic colony stimulating factor (G-CSF) on chemotherapy-induced neutropenia was evaluated in a patient with neuroblastoma. G-CSF was administered once daily as a subcutaneous injection at a dose level of 2 μg/kg/day for 10 days. Prompt recovery of granulocytes as well as total white blood cell count was obtained in comparison with previous chemotherapy not using G-CSF. G-CSF appears to be an appropriate means for increasing the number of granulocytes.
