抄録
Among the killed vaccines tested, the chrome-alum vaccine was most efficient in immune effect. The best immune conditions of experimental animals were obtained by the intraperitoneally twice treatments with each 2.8mg (dry weight) chrome-alum vaccine. But the immune effect of killed vaccine varied by the combination of the routes of treatment and challenge. And the most effective immunization was obtained by the combination of intraperitoneal treatment of killed vaccine and intraperitoneal challenge of the virulent S. enteritidis. This fact suggested the existence of local defence mechanisms in the abdominal cavity caused by the intraperitoneal immunization.
And the defence mechanisms of animals and the local defenec role in infection were discussed.
