ANTIGENIC SUBSTANCE IN URINE OF RABBITS INFECTED WITH SCHISTOSOMA JAPONICUM
1971 年 18 巻 1 号 p. 51-55
詳細
1971 年 18 巻 1 号 p. 51-55
The antigenic substance contained in urine of rabbits infected with S. japonicum was easily fractionated by the gel-filtration method using the Sephadex G-50 column. The fractionated substance showed distinct immunological reaction (double diffusion technique by Ouchterlony's and Oakley and Fulthorpe's methods) against the anti-S. japonicum rabbit serum, and was recognized to be the antigenic substance which originated from the adult worms. This is comparatively stable against heating and will partly pass through a cellophane membrane during dialysis. The active fraction obtained with Sephadex G-50 is still positive in Anthron's reaction and active after it was heated, dialyzed, and deproteinized. These results as well as UV absorption may show that this fraction has no close relationships to protein.
