Abstract
Using counter immunoelectrophoresis, an antigen in circulation of rabbits infected with Schistosoma japonicum was investigated. The sensitivity of counter immunoelectrophoresis was found to be 16 to 32 fold higher than that of ouchterlony test. The rapidity and simplicity seemed to be much superior to other serological tests. The antigen was detected in 22 of 24 infected rabbits with various periods of infection. The worm burden in negative cases were very low. In all infected rabbits, the antigen was constantly found since the appearance. The antigen titer in serum of each infected rabbits was significantly correlated with the worm burdens per body weight (r=0.70, p<0.01).
