The Kurume Medical Journal
Online ISSN : 1881-2090
Print ISSN : 0023-5679
ISSN-L : 0023-5679
GENETIC ANALYSIS OF POLYKARYOCYTOSIS BY HERPES SIMPLEX VIRUS
III. COMPLEMENTATION AND RECOMBINATION BETWEEN NONFUSING MUTANTS AND CONSTRUCTION OF A LINKAGE MAP WITH REGARD TO THE FUSION FUNCTION
SHIGERU YAMAMOTOHIDEFUMI KABUTA
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1977 Volume 24 Issue 3 Pages 163-172

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Abstract
Sixteen non-fusing mutants (γ) were isolated from virus (G) possessing fusion ability. Some mutant pairs complemented each other which resulted in an extensive cell fusion as original G virus, while the other mutant pairs did not. Thus, these mutants were classified into four complementation groups. By recombination analysis using eight γ mutants belonging to each complementation group, a linkage map has been constructed with regard to cell fusion. It has been demonstrated that four or possibly six cistrons are associated with the fusion event.
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