抄録
Computational analysis has been becoming useful approch to improving design of blood passages in membrane oxgenators. However,most of computationalanalysis methods focused on fluid dynamics in the blood layer to take into account a macro design of a blood passage. We focused on the gas transfer behaviors in a hollow fiber bundle of a commercial oxgenator using computational analysis method. A micro passage model is simulated arectangular part of a hollow fiber bundle. this computational model consists of parallel and staggerd arranged two hollow fiber membranes *(225 μm outer diameter and 165 μm inner diameter). Blood flows outside of hollow fobers in a direction of perpendicular to gas flow direction. Our computational analysis method deals coupled mass transfer and fluid dynamics including blood-gas reaction. In initial blood condition, partial oxygen pressure (PO2), partial carbon dioxide pressure (PCO2) and hemoglobin concentration (Hb) were set at 37.7 mmHg, 45.0 mmHg and 12.0 g/dL. In Initial gas condition, PO2 and PCO2 ere set at 713.0 mmHg and 0.0 mHg. In each results of PO2 and PCO2 distributions, maximaum values of PO2 and minimum values of PCO2 were demonstrated in the wake of a hollow fiber. Max PO2 and min PCO2 were 39.1 mmHg and 44.4 mmHg, 38.9 mmHg and 44.5 mmHg, and 38.7 mmHg and 44.6 mmHg at 1, 3, 5 L/min blood and gas flows, respectively.In conclusion, our computational analysis method is able to display distributions of PO2 and PCO2 in a micro passage among hollow fiber membranes.
