抄録
Surface Enhanced Raman Scattering (SERS) attracts much attention as a high sensitive analytical
method in microfluidics. Since a longer characteristic length of SERS active nanostructure is desirable
to improve sensitivity, the three-dimensional gold nanostructure (Au3D) was developed using a casting
method of convective self-assembly of binary particles under controlled interfaces. With obtained
sterically-bulky Au3D, a novel optofluidics system was demonstrated. Rapid and sensitive detection of
a 1 nM 4,4’-bipyridine aqueous solution was sufficiently performed with a good S/N ratio using a new
optofluidic device. This enhancement was estimated over 106 times compared to normal Raman
spectroscopy without Au3D.
