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40 巻, 12 号
「微小流体光学（Optofl uidics）：マイクロフォトニクスと流体の融合」解説小特集号
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「微小流体光学（Optofl uidics）：マイクロフォトニクスと流体の融合」解説小特集号
解説小特集
レーザー解説
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興 雄司, 宮崎 真佐也2012 年 40 巻 12 号 p. 911-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーPDF形式でダウンロード (250K) -
火原 彰秀2012 年 40 巻 12 号 p. 913-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーChemical and biological analysis based on micro- and nanofluidic systems have been investigated intensively because of such favorable properties as sample, reagent, waste, and space reductions. In the systems, two-phase flows were utilized for such chemical/biochemical applications as extractions and reactions. Since the specific interfacial area (surface-to-volume ratio) increases with confinement, the fluid interface between the two phases plays greater roles in the operations in micro/nano confined spaces than in laboratory-scale instruments. Fluid-interface measurement techniques for revealing molecular transport and interfacial properties are necessary for appropriately designing integrated twophase operation. However, few methods exist for the interface in micro/nano-systems. In this article, we investigated an optofluidic method for measuring the interfacial tension in micro/nano confined spaces based on capillary wave resonance and laser light scattering.抄録全体を表示PDF形式でダウンロード (2303K) -
杉岡 幸次2012 年 40 巻 12 号 p. 919-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーFemtosecond laser direct writing is a promising technique for fabricating optofluidics since it can modify the interior of glass in a spatially selective manner through multiphoton absorption. The unique ability of femtosecond laser direct writing to simultaneously alter the chemical and optical properties of glass opens up a new avenue for fabricating a variety of optofluidics since it can easily fabricate threedimensional microfluidics and optics inside glass. Optofluidics fabricated using femtosecond lasers have been used to determine the functions of living microorganisms, determine the concentrations of liquid samples, detect and manipulate single cells, and rapidly screen algae populations. This paper presents a review of optofluidics for biological analysis fabricated by femtosecond laser processing.抄録全体を表示PDF形式でダウンロード (3074K) -
遠藤 達郎2012 年 40 巻 12 号 p. 926-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーFor the future medical diagnostics, high sensitive and simplifi ed bioanalytical devices have been strongly desired. However, conventional bioanalytical devices such as enzyme-linked immunosrobent assays (ELISA) have several disadvantages such as high cost apparatus and sophisticated liquid handling. To overcome these disadvantages of conventional bioanalytical devices, we focused on the specifi c optical characteristics based on nanophotonics. Nanophotonics is the study of the behavior of light on the nanometer scale. And the optical characteristics will be drastically changed by the changing of surrounding refractive index. Based on nanophotonics, more simplifi ed baioanalytical devices can be developed. However, to develop the nanophotonics-based bioanalytical devices, high cost apparatus such as an electron beam lithography is required. In this study, to fabricate the nanophotonics-based devices cost-effectively, photonic crystal which is one of the nanophotonics-based devices was fabricated using“ Printable photonics technology” based on nanoimprint lithography.抄録全体を表示PDF形式でダウンロード (891K) -
福岡 隆夫, 内海 裕一2012 年 40 巻 12 号 p. 931-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーSurface Enhanced Raman Scattering (SERS) attracts much attention as a high sensitive analytical method in microfluidics. Since a longer characteristic length of SERS active nanostructure is desirable to improve sensitivity, the three-dimensional gold nanostructure (Au3D) was developed using a casting method of convective self-assembly of binary particles under controlled interfaces. With obtained sterically-bulky Au3D, a novel optofluidics system was demonstrated. Rapid and sensitive detection of a 1 nM 4,4’-bipyridine aqueous solution was sufficiently performed with a good S/N ratio using a new optofluidic device. This enhancement was estimated over 106 times compared to normal Raman spectroscopy without Au3D.抄録全体を表示PDF形式でダウンロード (1803K) -
佐藤 洋平2012 年 40 巻 12 号 p. 938-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーMicron-resolution particle image velocimetry (micro-PIV) and laser induced fluorescence (micro-LIF) have greatly contributed to development of microfluidic device and lab-on-a-chip. The precise control of spatial and temporal distribution of velocity, temperature, pH and ion concentration of microchannel flow will enhance the device performance. Moreover, nanoscale thermofluid sensing techniques have been developed using evanescent wave illumination. The spatial and temporal distribution of zeta potential at the microchannel wall was investigated by nanoscale laser induced fluorescence (nano-LIF). The effect of ion layer in the vicinity of wall on electroosmotic flow was examined by nano-resolution particle image velocimetry (nano-PIV). A novel non-intrusive sensing technique using spontaneous Raman scattering was proposed to investigate the ion motion in a microchannel flow.抄録全体を表示PDF形式でダウンロード (1869K) -
山下 健一, 宮崎 真佐也2012 年 40 巻 12 号 p. 942-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーMicrofl uidics and photonics are combined synergistically to form the fi eld referred to as “optofl uidics”. We herein reviewed the various techniques for the integration of optical elements into the microfl uidic device. Although optofl uidics involves integration of optics technique with fl uid-related technique, the basic technology for handling fl uid fl ow and light fl ow often differs. In this review, we introduce the device compositions of on-chip waveguide, tunable fl uidic lens, and color-space-time coding method using spatial and color fi lters, and also summarize the features of these techniques, such as high F-value and higher reliability attributed to fewer composition parts. The fusion of microfl uidics and optics could make simultaneous multiple measurements possible through single operation, a key factor that identifi es the usefulness of a device.抄録全体を表示PDF形式でダウンロード (633K)
レーザーオリジナル
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松浦 宏治, 渡辺 向陽, 加野 裕2012 年 40 巻 12 号 p. 947-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーObservation of cell adhesion site without chemical labeling contributes to the understanding of intracellular adhesion dynamics of biomolecules including integrin and other adhesion proteins. To satisfy the demands to investigate cell adhesion site without labeling, we employed a scanning localized surface plasmon microscopy (SLSPM) and observed the adhesion sites of the cell on a substrate with spatial resolution of 200 nm. By combining a non-scanning surface plasmon microscopy (SPM) and SLSPM, we observed a cell adhesion site and identifi ed the regions of interest. The main advantage of our system is that it has the highest spatial resolution among other SPM imaging systems, because size of an electric field distribution, which determines the spatial resolution, can be minimized by interference of surface plasmons excited with radially polarized light. In addition, we discuss the objectives to use the SLSPM and SPM systems reported by other groups for cell observation.抄録全体を表示PDF形式でダウンロード (568K) -
鍬光 浩太, 吉岡 宏晃, 片岡 周作, 鳴石 奈穂子, 田中 喜秀, 興 雄司2012 年 40 巻 12 号 p. 952-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーIntegratable and disposable solid-state dye lasers with a distributed feedback waveguide structure were studied. We fabricated the coupling of a methacrylate copolymer waveguide and similar substrate and demonstrated primitive fluorescence detection. We also developed laser integration on a beam-shaper with an optical fiber for fluidic chips of polydimethylsiloxane.抄録全体を表示PDF形式でダウンロード (2078K)
レーザーレクチャー
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石井 勝巳2012 年 40 巻 12 号 p. 963-
発行日: 2012年
公開日: 2020/08/26
ジャーナル フリーRecently, lasers are remarkably in use under various circumstances. The measurement of laser power and energy is the most fundamental one, and to know it quantitatively is very important for laser optimization by alignment, daily check as well as the min-max setting and the feedback system control in laser processing application, which leads to better quality control. So the interest in laser measurement is increasing more and more. In this paper I will pick up power meter and explain the principle, how to use and things to remember.抄録全体を表示PDF形式でダウンロード (701K)
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