レーザー研究
Online ISSN : 1349-6603
Print ISSN : 0387-0200
ISSN-L : 0387-0200
レーザー解説
離散波長量子カスケードレーザーを用いた血糖値測定
笠原 亮介大場 義浩和田 芳夫佐々木 俊英木野 彩子松浦 祐司
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2021 年 49 巻 9 号 p. 511-

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In recent years, noninvasive blood glucose measurement technologies have become more desirable. In this paper, we describe a method, which performs noninvasive blood glucose measurements, based on mid-infrared absorption spectroscopy, and uses only a few wavenumbers to unconditionally measure blood glucose levels in vivo. We identified the regression of blood glucose levels using only three wavenumbers, which were selected in a series cross validation technique. We demonstrated the performance of this model through correlations among different types of data and constructed an attenuated total reflection spectrometer with discrete fixed wavelengths using three distributed feedback quantum cascade lasers. To improve the accuracy of the glucose measurement, we examined the stabilization of the relative absorbance intensity between wavelengths by equalizing the illuminance distribution.
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